Cargando…

Matched Sizes of Activating and Inhibitory Receptor/Ligand Pairs Are Required for Optimal Signal Integration by Human Natural Killer Cells

It has been suggested that receptor-ligand complexes segregate or co-localise within immune synapses according to their size, and this is important for receptor signaling. Here, we set out to test the importance of receptor-ligand complex dimensions for immune surveillance of target cells by human N...

Descripción completa

Detalles Bibliográficos
Autores principales: Köhler, Karsten, Xiong, Shiqiu, Brzostek, Joanna, Mehrabi, Maryam, Eissmann, Philipp, Harrison, Alice, Cordoba, Shaun-Paul, Oddos, Stephane, Miloserdov, Vladimir, Gould, Keith, Burroughs, Nigel J., van der Merwe, Philip Anton, Davis, Daniel M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001952/
https://www.ncbi.nlm.nih.gov/pubmed/21179506
http://dx.doi.org/10.1371/journal.pone.0015374