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Phosphorylation of Lte1 by Cdk prevents polarized growth during mitotic arrest in S. cerevisiae

Lte1 is known as a regulator of mitotic progression in budding yeast. Here we demonstrate phosphorylation-dependent inhibition of polarized bud growth during G2/M by Lte1. Cla4 activity first localizes Lte1 to the polarity cap and thus specifically to the bud. This localization is a prerequisite for...

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Detalles Bibliográficos
Autores principales: Geymonat, Marco, Spanos, Adonis, Jensen, Sanne, Sedgwick, Steven G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002025/
https://www.ncbi.nlm.nih.gov/pubmed/21149565
http://dx.doi.org/10.1083/jcb.201005070