RNAi screen identifies a role for adaptor protein AP-3 in sorting to the regulated secretory pathway

The regulated release of proteins depends on their inclusion within large dense-core vesicles (LDCVs) capable of regulated exocytosis. LDCVs form at the trans-Golgi network (TGN), but the mechanism for protein sorting to this regulated secretory pathway (RSP) and the cytosolic machinery involved in...

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Detalles Bibliográficos
Autores principales: Asensio, Cédric S., Sirkis, Daniel W., Edwards, Robert H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002028/
https://www.ncbi.nlm.nih.gov/pubmed/21149569
http://dx.doi.org/10.1083/jcb.201006131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002028/
https://www.ncbi.nlm.nih.gov/pubmed/21149569
http://dx.doi.org/10.1083/jcb.201006131

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