Mad2 inhibits the mitotic kinesin MKlp2

We identified the mitotic kinesin-like protein 2 (MKlp2), a kinesin required for chromosome passenger complex (CPC)–mediated cytokinesis, as a target of the mitotic checkpoint protein Mad2. MKlp2 possesses a consensus Mad2-binding motif required for Mad2 binding. Mad2 prevents MKlp2 from loading ont...

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Detalles Bibliográficos
Autores principales: Lee, Sang Hyun, McCormick, Frank, Saya, Hideyuki
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002031/
https://www.ncbi.nlm.nih.gov/pubmed/21149564
http://dx.doi.org/10.1083/jcb.201003095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002031/
https://www.ncbi.nlm.nih.gov/pubmed/21149564
http://dx.doi.org/10.1083/jcb.201003095

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