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Formin follows function: a muscle-specific isoform of FHOD3 is regulated by CK2 phosphorylation and promotes myofibril maintenance

Members of the formin family are important for actin filament nucleation and elongation. We have identified a novel striated muscle–specific splice variant of the formin FHOD3 that introduces a casein kinase 2 (CK2) phosphorylation site. The specific targeting of muscle FHOD3 to the myofibrils in ca...

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Detalles Bibliográficos
Autores principales: Iskratsch, Thomas, Lange, Stephan, Dwyer, Joseph, Kho, Ay Lin, dos Remedios, Cris, Ehler, Elisabeth
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002041/
https://www.ncbi.nlm.nih.gov/pubmed/21149568
http://dx.doi.org/10.1083/jcb.201005060