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Formin follows function: a muscle-specific isoform of FHOD3 is regulated by CK2 phosphorylation and promotes myofibril maintenance
Members of the formin family are important for actin filament nucleation and elongation. We have identified a novel striated muscle–specific splice variant of the formin FHOD3 that introduces a casein kinase 2 (CK2) phosphorylation site. The specific targeting of muscle FHOD3 to the myofibrils in ca...
Autores principales: | Iskratsch, Thomas, Lange, Stephan, Dwyer, Joseph, Kho, Ay Lin, dos Remedios, Cris, Ehler, Elisabeth |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002041/ https://www.ncbi.nlm.nih.gov/pubmed/21149568 http://dx.doi.org/10.1083/jcb.201005060 |
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