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Increased male reproductive success in Ts65Dn “Down syndrome” mice

The Ts65Dn mouse is trisomic for orthologs of about half the genes on Hsa21. A number of phenotypes in these trisomic mice parallel those in humans with trisomy 21 (Down syndrome), including cognitive deficits due to hippocampal malfunction that are sufficiently similar to human that “therapies” dev...

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Detalles Bibliográficos
Autores principales: Moore, Clara S., Hawkins, Charles, Franca, Arianna, Lawler, Ann, Devenney, Benjamin, Das, Ishita, Reeves, Roger H.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002156/
https://www.ncbi.nlm.nih.gov/pubmed/21110029
http://dx.doi.org/10.1007/s00335-010-9300-8