TOPBP1 missense variant Arg309Cys and breast cancer in a German hospital-based case-control study

The DNA double strand break repair gene TOPBP1 has been suggested as a breast cancer susceptibility gene and a missense variant Arg309Cys was observed at elevated frequency in familial breast cancer cases compared to healthy controls from Finland. We found the Arg309Cys allele at a 13% carrier frequ...

Descripción completa

Detalles Bibliográficos
Autores principales: Blaut, Magda A, Bogdanova, Natalia V, Bremer, Michael, Karstens, Johann H, Hillemanns, Peter, Dörk, Thilo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002300/
https://www.ncbi.nlm.nih.gov/pubmed/21108795
http://dx.doi.org/10.1186/1477-5751-9-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002300/
https://www.ncbi.nlm.nih.gov/pubmed/21108795
http://dx.doi.org/10.1186/1477-5751-9-9

Ejemplares similares