Cargando…
TOPBP1 missense variant Arg309Cys and breast cancer in a German hospital-based case-control study
The DNA double strand break repair gene TOPBP1 has been suggested as a breast cancer susceptibility gene and a missense variant Arg309Cys was observed at elevated frequency in familial breast cancer cases compared to healthy controls from Finland. We found the Arg309Cys allele at a 13% carrier frequ...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002300/ https://www.ncbi.nlm.nih.gov/pubmed/21108795 http://dx.doi.org/10.1186/1477-5751-9-9 |