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Loss of heterozygosity and SOSTDC1 in adult and pediatric renal tumors

BACKGROUND: Deletions within the short arm of chromosome 7 are observed in approximately 25% of adult and 10% of Wilms pediatric renal tumors. Within Wilms tumors, the region of interest has been delineated to a 2-Mb minimal region that includes ten known genes. Two of these ten candidate genes, SOS...

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Detalles Bibliográficos
Autores principales: Blish, Kimberly R, Clausen, Kathryn A, Hawkins, Gregory A, Garvin, A Julian, Willingham, Mark C, Turner, Julie C, Torti, Frank M, Torti, Suzy V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002326/
https://www.ncbi.nlm.nih.gov/pubmed/21080955
http://dx.doi.org/10.1186/1756-9966-29-147