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Epigenetic control of the basal-like gene expression profile via Interleukin-6 in breast cancer cells

BACKGROUND: Basal-like carcinoma are aggressive breast cancers that frequently carry p53 inactivating mutations, lack estrogen receptor-α (ERα) and express the cancer stem cell markers CD133 and CD44. These tumors also over-express Interleukin 6 (IL-6), a pro-inflammatory cytokine that stimulates th...

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Detalles Bibliográficos
Autores principales: D'Anello, Laura, Sansone, Pasquale, Storci, Gianluca, Mitrugno, Valentina, D'Uva, Gabriele, Chieco, Pasquale, Bonafé, Massimiliano
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002335/
https://www.ncbi.nlm.nih.gov/pubmed/21092249
http://dx.doi.org/10.1186/1476-4598-9-300