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Induction of heme oxygenase-1 attenuates lipopolysaccharide-induced cyclooxygenase-2 expression in mouse brain endothelial cells

BACKGROUND: Prostaglandin E(2 )(PGE(2)), an arachidonic acid metabolite converted by cyclooxygenase-2 (COX-2), plays important roles in the regulation of endothelial functions in response to bacterial infection. The enzymatic activity of COX-2 can be down-regulated by heme oxygenase-1 (HO-1) inducti...

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Detalles Bibliográficos
Autores principales:	Shih, Ruey-Horng, Yang, Chuen-Mao
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002338/ https://www.ncbi.nlm.nih.gov/pubmed/21118574 http://dx.doi.org/10.1186/1742-2094-7-86

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