Localization of uPAR and MMP-9 in lipid rafts is critical for migration, invasion and angiogenesis in human breast cancer cells

BACKGROUND: uPAR and MMP-9, which play critical roles in tumor cell invasion, migration and angiogenesis, have been shown to be associated with lipid rafts. METHODS: To investigate whether cholesterol could regulate uPAR and MMP-9 in breast carcinoma, we used MβCD (methyl beta cyclodextrin, which ex...

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Detalles Bibliográficos
Autores principales: Raghu, Hari, Sodadasu, Prasanna Kumar, Malla, Rama Rao, Gondi, Christopher S, Estes, Norman, Rao, Jasti S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002355/
https://www.ncbi.nlm.nih.gov/pubmed/21106094
http://dx.doi.org/10.1186/1471-2407-10-647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002355/
https://www.ncbi.nlm.nih.gov/pubmed/21106094
http://dx.doi.org/10.1186/1471-2407-10-647

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