KRAS analysis in colorectal carcinoma: Analytical aspects of Pyrosequencing and allele-specific PCR in clinical practice

BACKGROUND: Epidermal growth factor receptor inhibitor therapy is now approved for treatment of metastatic colorectal carcinomas (CRC) in patients with tumors lacking KRAS mutations. Several procedures to detect KRAS mutations have been developed. However, the analytical sensitivity and specificity...

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Detalles Bibliográficos
Autores principales: Sundström, Magnus, Edlund, Karolina, Lindell, Monica, Glimelius, Bengt, Birgisson, Helgi, Micke, Patrick, Botling, Johan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002357/
https://www.ncbi.nlm.nih.gov/pubmed/21122130
http://dx.doi.org/10.1186/1471-2407-10-660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002357/
https://www.ncbi.nlm.nih.gov/pubmed/21122130
http://dx.doi.org/10.1186/1471-2407-10-660

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