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Investigating dynamic and energetic determinants of protein nucleic acid recognition: analysis of the zinc finger zif268-DNA complexes

BACKGROUND: Protein-DNA recognition underlies fundamental biological processes ranging from transcription to replication and modification. Herein, we present a computational study of the sequence modulation of internal dynamic properties and of intraprotein networks of aminoacid interactions that de...

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Detalles Bibliográficos
Autores principales: Torella, Rubben, Moroni, Elisabetta, Caselle, Michele, Morra, Giulia, Colombo, Giorgio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002361/
https://www.ncbi.nlm.nih.gov/pubmed/21106075
http://dx.doi.org/10.1186/1472-6807-10-42