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Sampling the conformation of protein surface residues for flexible protein docking

BACKGROUND: The problem of determining the physical conformation of a protein dimer, given the structures of the two interacting proteins in their unbound state, is a difficult one. The location of the docking interface is determined largely by geometric complementarity, but finding complementary ge...

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Detalles Bibliográficos
Autores principales: Francis-Lyon, Patricia, Gu, Shengyin, Hass, Joel, Amenta, Nina, Koehl, Patrice
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002368/
https://www.ncbi.nlm.nih.gov/pubmed/21092317
http://dx.doi.org/10.1186/1471-2105-11-575