Dephosphorylation of Nucleophosmin by PP1β Facilitates pRB Binding and Consequent E2F1-dependent DNA Repair

Nucleophosmin (NPM) is an important phosphoprotein with pleiotropic functions in various cellular processes. Although phosphorylation has been postulated as an important functional determinant, possible regulatory roles of this modification on NPM are not fully characterized. Here, we find that NPM...

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Detalles Bibliográficos
Autores principales: Lin, Chiao Yun, Tan, Bertrand Chin-Ming, Liu, Hsuan, Shih, Chii-Jiun, Chien, Kun-Yi, Lin, Chih-Li, Yung, Benjamin Yat-Ming
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002393/
https://www.ncbi.nlm.nih.gov/pubmed/20962268
http://dx.doi.org/10.1091/mbc.E10-03-0239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002393/
https://www.ncbi.nlm.nih.gov/pubmed/20962268
http://dx.doi.org/10.1091/mbc.E10-03-0239

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