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Formulation Optimization of Hydrodynamically Balanced Oral Controlled Release Bioadhesive Tablets of Tramadol Hydrochloride

The directly compressible floating-bioadhesive tablets of tramadol were formulated using varying amounts Carbopol 971P (CP) and hydroxy-propylmethyl cellulose (HPMC), along with other requisite excipients. In vitro drug release profile, floatational characteristics and ex vivo bioadhesive strength u...

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Detalles Bibliográficos
Autores principales: Singh, Bhupinder, Rani, Ashu, Babita, Ahuja, Naveen, Kapil, Rishi
Formato: Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002789/
https://www.ncbi.nlm.nih.gov/pubmed/21179349
http://dx.doi.org/10.3797/scipharm.1001-04