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Formulation Optimization of Hydrodynamically Balanced Oral Controlled Release Bioadhesive Tablets of Tramadol Hydrochloride

The directly compressible floating-bioadhesive tablets of tramadol were formulated using varying amounts Carbopol 971P (CP) and hydroxy-propylmethyl cellulose (HPMC), along with other requisite excipients. In vitro drug release profile, floatational characteristics and ex vivo bioadhesive strength u...

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Detalles Bibliográficos
Autores principales:	Singh, Bhupinder, Rani, Ashu, Babita, Ahuja, Naveen, Kapil, Rishi
Formato:	Texto
Lenguaje:	English
Publicado:	Österreichische Apotheker-Verlagsgesellschaft 2010
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002789/ https://www.ncbi.nlm.nih.gov/pubmed/21179349 http://dx.doi.org/10.3797/scipharm.1001-04

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