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Antidepressant/Anxiolytic and Anti-Nociceptive Effects of Novel 2-Substituted 1,4-Benzodiazepine-2-ones

Oxazepam (4a) has been used as overall starting material in the synthesis of novel 2-substituted 1,4-benzodiazepines. By reacting Oxazepam 4a with commercially available hydrazines, hydrazides, semicarbazide, aminoguanidine and N,N-dimethylamino aniline in ethanol under acetic conditions, a series o...

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Detalles Bibliográficos
Autores principales: Singh, Harjit, Sattayasai, Jintana, Lattmann, Pornthip, Boonprakob, Yodchai, Lattmann, Eric
Formato: Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002793/
https://www.ncbi.nlm.nih.gov/pubmed/21179341
http://dx.doi.org/10.3797/scipharm.1004-12