Method Development and Validation of Montelukast in Human Plasma by HPLC Coupled with ESI-MS/MS: Application to a Bioequivalence Study

A simple, sensitive, and specific LC-ESI–MS/MS method for quantification of Montelukast (MO) in human plasma using Montelukast-d(6) (MOD6) as an internal standard (IS) is discussed here. Chromatographic separation was performed on YMC-pack pro C(18), 50 x 4.6 mm, S-3 μm column with an isocratic mobi...

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Detalles Bibliográficos
Autores principales: Challa, Balasekhara Reddy, Awen, Bahlul Z., Chandu, Babu Rao, Khagga, Mukkanti, Kotthapalli, Chandrasekhar Bannoth
Formato: Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2010
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002811/
https://www.ncbi.nlm.nih.gov/pubmed/21179354
http://dx.doi.org/10.3797/scipharm.1002-07

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002811/
https://www.ncbi.nlm.nih.gov/pubmed/21179354
http://dx.doi.org/10.3797/scipharm.1002-07

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