Cargando…

Method Development and Validation of Montelukast in Human Plasma by HPLC Coupled with ESI-MS/MS: Application to a Bioequivalence Study

A simple, sensitive, and specific LC-ESI–MS/MS method for quantification of Montelukast (MO) in human plasma using Montelukast-d(6) (MOD6) as an internal standard (IS) is discussed here. Chromatographic separation was performed on YMC-pack pro C(18), 50 x 4.6 mm, S-3 μm column with an isocratic mobi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Challa, Balasekhara Reddy, Awen, Bahlul Z., Chandu, Babu Rao, Khagga, Mukkanti, Kotthapalli, Chandrasekhar Bannoth
Formato:	Texto
Lenguaje:	English
Publicado:	Österreichische Apotheker-Verlagsgesellschaft 2010
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002811/ https://www.ncbi.nlm.nih.gov/pubmed/21179354 http://dx.doi.org/10.3797/scipharm.1002-07

Ejemplares similares

Bioequivalance and pharmacokinetic study of febuxostat in human plasma by using LC-MS/MS with liquid liquid extraction method
por: Chandu, Babu Rao, et al.
Publicado: (2013)

Development and Validation of Amisulpride in Human Plasma by HPLC Coupled with Tandem Mass Spectrometry and its Application to a Pharmacokinetic Study
por: Mogili, Ramakotaiah, et al.
Publicado: (2011)

A validated LC–MS/MS method for the determination of tolterodine and its metabolite in rat plasma and application to pharmacokinetic study
por: Shaik, Rihana Parveen, et al.
Publicado: (2013)

Bioanalytical method development and validation of milnacipran in rat plasma by LC–MS/MS detection and its application to a pharmacokinetic study
por: Kanala, Kanchanamala, et al.
Publicado: (2013)

Method Development and Validation of Almotriptan in Human Plasma by HPLC Tandem Mass Spectrometry: Application to Pharmacokinetic Study
por: Ravikumar, Konda, et al.
Publicado: (2012)

Fast and Sensitive HPLC-ESI-MS/MS Method for Etoricoxib Quantification in Human Plasma and Application to Bioequivalence Study
por: Loh, Gabriel Onn Kit, et al.
Publicado: (2022)

Quantification of sibutramine and its two metabolites in human plasma by LC–ESI-MS/MS and its application in a bioequivalence study
por: Ponnuru, Venkata Suresh, et al.
Publicado: (2012)

Quantification of tolvaptan in rabbit plasma by LC–MS/MS: Application to a pharmacokinetic study()
por: Moola, Kumar S., et al.
Publicado: (2015)

HPLC-ESI-MS/MS of Imidazole Alkaloids in Pilocarpus microphyllus
por: Sawaya, Alexandra CH F, et al.
Publicado: (2008)

Phenolic Profiling of Duchesnea indica Combining Macroporous Resin Chromatography (MRC) with HPLC-ESI-MS/MS and ESI-IT-MS
por: Zhu, Mingzhi, et al.
Publicado: (2015)

Fabric phase sorptive extraction coupled with UPLC-ESI-MS/MS method for fast and sensitive quantitation of tadalafil in a bioequivalence study
por: Ahmed, Sameh A., et al.
Publicado: (2022)

Bioaffinity ultrafiltration coupled with HPLC-ESI-MS/MS for screening potential α-glucosidase inhibitors from pomegranate peel
por: Shi, Rujie, et al.
Publicado: (2022)

Determination of Puquitinib in Human Plasma by HPLC–ESI MS/MS: Application to Pharmacokinetic Study
por: Zhan, Jing, et al.
Publicado: (2018)

Rapid Characterization of Triterpene Saponins from Zornia brasiliensis by HPLC-ESI-MS/MS
por: Nascimento, Yuri Mangueira, et al.
Publicado: (2019)

Investigation of the bioequivalence of montelukast chewable tablets after a single oral administration using a validated LC-MS/MS method
por: Zaid, Abdel Naser, et al.
Publicado: (2015)

Determination of Dapoxetine Hydrochloride in Human Plasma by HPLC–MS/MS and Its Application in a Bioequivalence Study
por: Zhang, Xin, et al.
Publicado: (2022)

HPLC–UV–ESI MS/MS identification of the color constituents of sawwort (Serratula tinctoria L.)
por: Lech, Katarzyna, et al.
Publicado: (2014)

HPLC-PDA-ESI-MS/MS Profiling and Anti-Biofilm Potential of Eucalyptus sideroxylon Flowers
por: Okba, Mona M., et al.
Publicado: (2021)

Screening and Identifying Antioxidative Components in Ginkgo biloba Pollen by DPPH-HPLC-PAD Coupled with HPLC-ESI-MS(2)
por: Qiu, Jiying, et al.
Publicado: (2017)

Bioanalytical Method Development and Validation of Memantine in Human Plasma by High Performance Liquid Chromatography with Tandem Mass Spectrometry: Application to Bioequivalence Study
por: Konda, Ravi Kumar, et al.
Publicado: (2012)

Identification and Analysis of Amygdalin, Neoamygdalin and Amygdalin Amide in Different Processed Bitter Almonds by HPLC-ESI-MS/MS and HPLC-DAD
por: Xu, Shuya, et al.
Publicado: (2017)

Determining the degradation efficiency and mechanisms of ethyl violet using HPLC-PDA-ESI-MS and GC-MS
por: Chung, Wen-Hsin, et al.
Publicado: (2012)

Identification and Quantification of 29 Active Substances by HPLC–ESI-MS/MS in Lyophilized Swine Manure Samples
por: Nebot, Carolina, et al.
Publicado: (2022)

Characterization of Flavonoids and Phenolic Acids in Myrcia bella Cambess. Using FIA-ESI-IT-MS(n) and HPLC-PAD-ESI-IT-MS Combined with NMR
por: Saldanha, Luiz L., et al.
Publicado: (2013)

Simultaneous determination of ezetimibe and simvastatin in rat plasma by stable-isotope dilution LC-ESI–MS/MS and its application to a pharmacokinetic study
por: Karanam, Sireesha R., et al.
Publicado: (2014)

Insight on physicochemical properties governing peptide MS1 response in HPLC-ESI-MS/MS: A deep learning approach
por: Abdul-Khalek, Naim, et al.
Publicado: (2023)

Investigation into mercury bound to biothiols: structural identification using ESI–ion-trap MS and introduction of a method for their HPLC separation with simultaneous detection by ICP-MS and ESI-MS
por: Krupp, Eva M., et al.
Publicado: (2008)

Quantification of desloratadine in human plasma by LC-ESI-MS/MS and application to a pharmacokinetic study
por: Ponnuru, Venkata Suresh, et al.
Publicado: (2012)

Correction: Determining the degradation efficiency and mechanisms of ethyl violet using HPLC-PDA-ESI-MS and GC-MS
por: Lu, Chung-Shin, et al.
Publicado: (2014)

Identification and characterization of phenolics and terpenoids from ethanolic extracts of Phyllanthus species by HPLC-ESI-QTOF-MS/MS
por: Kumar, Sunil, et al.
Publicado: (2017)

Regioisomer-independent quantification of fatty acid oxidation products by HPLC-ESI-MS/MS analysis of sodium adducts
por: Ahern, Katelyn W., et al.
Publicado: (2019)

Targeted phenolic profile of radler beers by HPLC-ESI-MS/MS: the added value of hesperidin to beer antioxidants
por: Di Matteo, Paola, et al.
Publicado: (2022)

Polyphenol Composition by HPLC-DAD-(ESI-)MS/MS and Bioactivities of Extracts from Grape Agri-Food Wastes
por: Ueda, Jonata M., et al.
Publicado: (2023)

Method development and validation of Guanfacine in rat plasma by liquid chromatography–tandem mass spectrometry: Application to a pharmacokinetic study
por: Goparaju, Suryanarayana Murthy, et al.
Publicado: (2013)

HPLC-ESI-MS method for C(60) fullerene mitochondrial content quantification
por: Grebinyk, Anna, et al.
Publicado: (2018)

Quantitative Analysis of Polysaccharide Composition in Polyporus umbellatus by HPLC–ESI–TOF–MS
por: Guo, Ning, et al.
Publicado: (2019)

HPLC-UV, MALDI-TOF-MS and ESI-MS/MS Analysis of the Mechlorethamine DNA Crosslink at a Cytosine-Cytosine Mismatch Pair
por: Rojsitthisak, Pornchai, et al.
Publicado: (2011)

Changes of Metabolomic Profile in Helianthus annuus under Exposure to Chromium(VI) Studied by capHPLC-ESI-QTOF-MS and MS/MS
por: Gonzalez Ibarra, Alan Alexander, et al.
Publicado: (2017)

A Comparative Study on Analysis of Ginsenosides in American Ginseng Root Residue by HPLC-DAD-ESI-MS and UPLC-HRMS-MS/MS
por: Hsu, Bo-Yang, et al.
Publicado: (2022)

Synthesis, isolation, identification and characterization of new process-related impurity in isoproterenol hydrochloride by HPLC, LC/ESI-MS and NMR
por: Kumar, Neeraj, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_olk9lghporn5iagjjcq4gildac