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Grifonin-1: A Small HIV-1 Entry Inhibitor Derived from the Algal Lectin, Griffithsin

BACKGROUND: Griffithsin, a 121-residue protein isolated from a red algal Griffithsia sp., binds high mannose N-linked glycans of virus surface glycoproteins with extremely high affinity, a property that allows it to prevent the entry of primary isolates and laboratory strains of T- and M-tropic HIV-...

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Detalles Bibliográficos
Autores principales: Micewicz, Ewa D., Cole, Amy L., Jung, Chun-Ling, Luong, Hai, Phillips, Martin L., Pratikhya, Pratikhya, Sharma, Shantanu, Waring, Alan J., Cole, Alexander M., Ruchala, Piotr
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002932/
https://www.ncbi.nlm.nih.gov/pubmed/21179548
http://dx.doi.org/10.1371/journal.pone.0014360