Inhibition of Stearoyl-CoA Desaturase 1 Expression Induces CHOP-Dependent Cell Death in Human Cancer Cells

BACKGROUND: Cancer cells present a sustained de novo fatty acid synthesis with an increase of saturated and monounsaturated fatty acid (MUFA) production. This change in fatty acid metabolism is associated with overexpression of stearoyl-CoA desaturase 1 (Scd1), which catalyses the transformation of...

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Detalles Bibliográficos
Autores principales: Minville-Walz, Mélaine, Pierre, Anne-Sophie, Pichon, Laurent, Bellenger, Sandrine, Fèvre, Cécile, Bellenger, Jérôme, Tessier, Christian, Narce, Michel, Rialland, Mickaël
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002938/
https://www.ncbi.nlm.nih.gov/pubmed/21179554
http://dx.doi.org/10.1371/journal.pone.0014363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002938/
https://www.ncbi.nlm.nih.gov/pubmed/21179554
http://dx.doi.org/10.1371/journal.pone.0014363

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