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A Transient Transgenic RNAi Strategy for Rapid Characterization of Gene Function during Embryonic Development

RNA interference (RNAi) is a powerful strategy for studying the phenotypic consequences of reduced gene expression levels in model systems. To develop a method for the rapid characterization of the developmental consequences of gene dysregulation, we tested the use of RNAi for “transient transgenic”...

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Detalles Bibliográficos
Autores principales: Bjork, Bryan C., Fujiwara, Yuko, Davis, Shannon W., Qiu, Haiyan, Saunders, Thomas L., Sandy, Peter, Orkin, Stuart, Camper, Sally A., Beier, David R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002952/
https://www.ncbi.nlm.nih.gov/pubmed/21179568
http://dx.doi.org/10.1371/journal.pone.0014375