Modeling the Evolution of Regulatory Elements by Simultaneous Detection and Alignment with Phylogenetic Pair HMMs

The computational detection of regulatory elements in DNA is a difficult but important problem impacting our progress in understanding the complex nature of eukaryotic gene regulation. Attempts to utilize cross-species conservation for this task have been hampered both by evolutionary changes of fun...

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Detalles Bibliográficos
Autores principales: Majoros, William H., Ohler, Uwe
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002982/
https://www.ncbi.nlm.nih.gov/pubmed/21187896
http://dx.doi.org/10.1371/journal.pcbi.1001037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002982/
https://www.ncbi.nlm.nih.gov/pubmed/21187896
http://dx.doi.org/10.1371/journal.pcbi.1001037

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