HIV-1 Envelope Subregion Length Variation during Disease Progression

The V3 loop of the HIV-1 Env protein is the primary determinant of viral coreceptor usage, whereas the V1V2 loop region is thought to influence coreceptor binding and participate in shielding of neutralization-sensitive regions of the Env glycoprotein gp120 from antibody responses. The functional pr...

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Detalles Bibliográficos
Autores principales: Curlin, Marcel E., Zioni, Rafael, Hawes, Stephen E., Liu, Yi, Deng, Wenjie, Gottlieb, Geoffrey S., Zhu, Tuofu, Mullins, James I.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002983/
https://www.ncbi.nlm.nih.gov/pubmed/21187897
http://dx.doi.org/10.1371/journal.ppat.1001228