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HIV-1 Envelope Subregion Length Variation during Disease Progression
The V3 loop of the HIV-1 Env protein is the primary determinant of viral coreceptor usage, whereas the V1V2 loop region is thought to influence coreceptor binding and participate in shielding of neutralization-sensitive regions of the Env glycoprotein gp120 from antibody responses. The functional pr...
Autores principales: | Curlin, Marcel E., Zioni, Rafael, Hawes, Stephen E., Liu, Yi, Deng, Wenjie, Gottlieb, Geoffrey S., Zhu, Tuofu, Mullins, James I. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002983/ https://www.ncbi.nlm.nih.gov/pubmed/21187897 http://dx.doi.org/10.1371/journal.ppat.1001228 |
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