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Mycobacterium tuberculosis Eis Regulates Autophagy, Inflammation, and Cell Death through Redox-dependent Signaling

The “enhanced intracellular survival” (eis) gene of Mycobacterium tuberculosis (Mtb) is involved in the intracellular survival of M. smegmatis. However, its exact effects on host cell function remain elusive. We herein report that Mtb Eis plays essential roles in modulating macrophage autophagy, inf...

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Detalles Bibliográficos
Autores principales: Shin, Dong-Min, Jeon, Bo-Young, Lee, Hye-Mi, Jin, Hyo Sun, Yuk, Jae-Min, Song, Chang-Hwa, Lee, Sang-Hee, Lee, Zee-Won, Cho, Sang-Nae, Kim, Jin-Man, Friedman, Richard L., Jo, Eun-Kyeong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002989/
https://www.ncbi.nlm.nih.gov/pubmed/21187903
http://dx.doi.org/10.1371/journal.ppat.1001230