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Mycobacterium tuberculosis Eis Regulates Autophagy, Inflammation, and Cell Death through Redox-dependent Signaling
The “enhanced intracellular survival” (eis) gene of Mycobacterium tuberculosis (Mtb) is involved in the intracellular survival of M. smegmatis. However, its exact effects on host cell function remain elusive. We herein report that Mtb Eis plays essential roles in modulating macrophage autophagy, inf...
Autores principales: | Shin, Dong-Min, Jeon, Bo-Young, Lee, Hye-Mi, Jin, Hyo Sun, Yuk, Jae-Min, Song, Chang-Hwa, Lee, Sang-Hee, Lee, Zee-Won, Cho, Sang-Nae, Kim, Jin-Man, Friedman, Richard L., Jo, Eun-Kyeong |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002989/ https://www.ncbi.nlm.nih.gov/pubmed/21187903 http://dx.doi.org/10.1371/journal.ppat.1001230 |
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