Cargando…

NleC, a Type III Secretion Protease, Compromises NF-κB Activation by Targeting p65/RelA

The NF-κB signaling pathway is central to the innate and adaptive immune responses. Upon their detection of pathogen-associated molecular patterns, Toll-like receptors on the cell surface initiate signal transduction and activate the NF-κB pathway, leading to the production of a wide array of inflam...

Descripción completa

Detalles Bibliográficos
Autores principales: Yen, Hilo, Ooka, Tadasuke, Iguchi, Atsushi, Hayashi, Tetsuya, Sugimoto, Nakaba, Tobe, Toru
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002990/
https://www.ncbi.nlm.nih.gov/pubmed/21187904
http://dx.doi.org/10.1371/journal.ppat.1001231