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NleC, a Type III Secretion Protease, Compromises NF-κB Activation by Targeting p65/RelA
The NF-κB signaling pathway is central to the innate and adaptive immune responses. Upon their detection of pathogen-associated molecular patterns, Toll-like receptors on the cell surface initiate signal transduction and activate the NF-κB pathway, leading to the production of a wide array of inflam...
Autores principales: | Yen, Hilo, Ooka, Tadasuke, Iguchi, Atsushi, Hayashi, Tetsuya, Sugimoto, Nakaba, Tobe, Toru |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002990/ https://www.ncbi.nlm.nih.gov/pubmed/21187904 http://dx.doi.org/10.1371/journal.ppat.1001231 |
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