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Structural and Functional Studies of Nonstructural Protein 2 of the Hepatitis C Virus Reveal Its Key Role as Organizer of Virion Assembly

Non-structural protein 2 (NS2) plays an important role in hepatitis C virus (HCV) assembly, but neither the exact contribution of this protein to the assembly process nor its complete structure are known. In this study we used a combination of genetic, biochemical and structural methods to decipher...

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Detalles Bibliográficos
Autores principales: Jirasko, Vlastimil, Montserret, Roland, Lee, Ji Young, Gouttenoire, Jérôme, Moradpour, Darius, Penin, Francois, Bartenschlager, Ralf
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002993/
https://www.ncbi.nlm.nih.gov/pubmed/21187906
http://dx.doi.org/10.1371/journal.ppat.1001233