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Structural and Functional Studies of Nonstructural Protein 2 of the Hepatitis C Virus Reveal Its Key Role as Organizer of Virion Assembly
Non-structural protein 2 (NS2) plays an important role in hepatitis C virus (HCV) assembly, but neither the exact contribution of this protein to the assembly process nor its complete structure are known. In this study we used a combination of genetic, biochemical and structural methods to decipher...
Autores principales: | Jirasko, Vlastimil, Montserret, Roland, Lee, Ji Young, Gouttenoire, Jérôme, Moradpour, Darius, Penin, Francois, Bartenschlager, Ralf |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002993/ https://www.ncbi.nlm.nih.gov/pubmed/21187906 http://dx.doi.org/10.1371/journal.ppat.1001233 |
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