Dishevelled-3 C-terminal His single amino acid repeats are obligate for Wnt5a activation of non-canonical signaling

BACKGROUND: The Wnt non-canonical pathway (Wnt5a > Frizzled-2 > cyclic GMP phosphodiesterase/Ca(2+)-mobilization pathway regulates the activation of NF-AT) is mediated by three mammalian Dishevelleds (Dvl1, Dvl2, and Dvl3) and the role of the C-terminal region unique to Dvl3 was interrogated....

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Detalles Bibliográficos
Autores principales: Ma, Li, Wang, Ying, Malbon, Craig C, Wang, Hsien-yu
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003240/
https://www.ncbi.nlm.nih.gov/pubmed/21092292
http://dx.doi.org/10.1186/1750-2187-5-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003240/
https://www.ncbi.nlm.nih.gov/pubmed/21092292
http://dx.doi.org/10.1186/1750-2187-5-19

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