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Sensitization of capsaicin and icilin responses in oxaliplatin treated adult rat DRG neurons
BACKGROUND: Oxaliplatin chemotherapy induced neuropathy is a dose related cumulative toxicity that manifests as tingling, numbness, and chronic pain, compromising the quality of life and leading to discontinued chemotherapy. Patients report marked hypersensitivity to cold stimuli at early stages of...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003244/ https://www.ncbi.nlm.nih.gov/pubmed/21106058 http://dx.doi.org/10.1186/1744-8069-6-82 |