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Sensitization of capsaicin and icilin responses in oxaliplatin treated adult rat DRG neurons

BACKGROUND: Oxaliplatin chemotherapy induced neuropathy is a dose related cumulative toxicity that manifests as tingling, numbness, and chronic pain, compromising the quality of life and leading to discontinued chemotherapy. Patients report marked hypersensitivity to cold stimuli at early stages of...

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Detalles Bibliográficos
Autores principales: Anand, Uma, Otto, William R, Anand, Praveen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003244/
https://www.ncbi.nlm.nih.gov/pubmed/21106058
http://dx.doi.org/10.1186/1744-8069-6-82