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The tumor-associated EpCAM regulates morphogenetic movements through intracellular signaling

Epithelial cell adhesion molecule (EpCAM) is best known as a tumor-associated protein highly expressed in carcinomas. The function of this cell surface protein during embryonic development and its potential role in cancer are still poorly understood. We identified EpCAM in a gain-of-function screen...

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Detalles Bibliográficos
Autores principales: Maghzal, Nadim, Vogt, Emily, Reintsch, Wolfgang, Fraser, James S., Fagotto, François
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003323/
https://www.ncbi.nlm.nih.gov/pubmed/20974811
http://dx.doi.org/10.1083/jcb.201004074