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Caveolin-1 is ubiquitinated and targeted to intralumenal vesicles in endolysosomes for degradation

Caveolae are long-lived plasma membrane microdomains composed of caveolins, cavins, and a cholesterol-rich membrane. Little is known about how caveolae disassemble and how their coat components are degraded. We studied the degradation of caveolin-1 (CAV1), a major caveolar protein, in CV1 cells. CAV...

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Detalles Bibliográficos
Autores principales: Hayer, Arnold, Stoeber, Miriam, Ritz, Danilo, Engel, Sabrina, Meyer, Hemmo H., Helenius, Ari
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003328/
https://www.ncbi.nlm.nih.gov/pubmed/21041450
http://dx.doi.org/10.1083/jcb.201003086