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Resting State Orai1 Diffuses as Homotetramer in the Plasma Membrane of Live Mammalian Cells

Store-operated calcium entry is essential for many signaling processes in nonexcitable cells. The best studied store-operated calcium current is the calcium release-activated calcium (CRAC) current in T-cells and mast cells, with Orai1 representing the essential pore forming subunit. Although it is...

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Detalles Bibliográficos
Autores principales: Madl, Josef, Weghuber, Julian, Fritsch, Reinhard, Derler, Isabella, Fahrner, Marc, Frischauf, Irene, Lackner, Barbara, Romanin, Christoph, Schütz, Gerhard J.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003411/
https://www.ncbi.nlm.nih.gov/pubmed/20961852
http://dx.doi.org/10.1074/jbc.M110.177881