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Resting State Orai1 Diffuses as Homotetramer in the Plasma Membrane of Live Mammalian Cells
Store-operated calcium entry is essential for many signaling processes in nonexcitable cells. The best studied store-operated calcium current is the calcium release-activated calcium (CRAC) current in T-cells and mast cells, with Orai1 representing the essential pore forming subunit. Although it is...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003411/ https://www.ncbi.nlm.nih.gov/pubmed/20961852 http://dx.doi.org/10.1074/jbc.M110.177881 |