The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases

Substrates of the N-end rule pathway are recognized by the Ubr1 E3 ubiquitin ligase through their destabilizing N-terminal residues. Our previous work showed that the Ubr1 E3 and the Ufd4 E3 co-target an internal degron of the Mgt1 DNA repair protein. Ufd4 is an E3 of the ubiquitin-fusion degradatio...

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Detalles Bibliográficos
Autores principales: Hwang, Cheol-Sang, Shemorry, Anna, Auerbach, Daniel, Varshavsky, Alexander
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003441/
https://www.ncbi.nlm.nih.gov/pubmed/21076411
http://dx.doi.org/10.1038/ncb2121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003441/
https://www.ncbi.nlm.nih.gov/pubmed/21076411
http://dx.doi.org/10.1038/ncb2121

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