CTLA4-Ig interacts with cultured synovial macrophages from rheumatoid arthritis patients and downregulates cytokine production

INTRODUCTION: Co-stimulatory signal B7(CD80/CD86):CD28 is needed in order to activate T cells in immune response. Cytotoxic T lymphocyte-associated antigen-4-immunoglobulin (CTLA4-Ig) binding to the B7 molecules on antigen-presenting cells downregulates this activation and represents a recent biolog...

Descripción completa

Detalles Bibliográficos
Autores principales: Cutolo, Maurizio, Soldano, Stefano, Montagna, Paola, Sulli, Alberto, Seriolo, Bruno, Villaggio, Barbara, Triolo, Pierfranco, Clerico, Paolo, Felli, Lamberto, Brizzolara, Renata
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003520/
https://www.ncbi.nlm.nih.gov/pubmed/19930661
http://dx.doi.org/10.1186/ar2865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003520/
https://www.ncbi.nlm.nih.gov/pubmed/19930661
http://dx.doi.org/10.1186/ar2865

Ejemplares similares