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Local expression of tumor necrosis factor-receptor 1:immunoglobulin G can induce salivary gland dysfunction in a murine model of Sjögren's syndrome

INTRODUCTION: Tumor necrosis factor is a pleiotropic cytokine with potent immune regulatory functions. Although tumor necrosis factor inhibitors have demonstrated great utility in treating other autoimmune diseases, such as rheumatoid arthritis, there are conflicting results in Sjögren's syndro...

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Detalles Bibliográficos
Autores principales: Vosters, Jelle L, Yin, Hongen, Roescher, Nienke, Kok, Marc R, Tak, Paul P, Chiorini, John A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003528/
https://www.ncbi.nlm.nih.gov/pubmed/20003451
http://dx.doi.org/10.1186/ar2888