A combination of methotrexate and zoledronic acid prevents bone erosions and systemic bone mass loss in collagen induced arthritis

INTRODUCTION: Osteoclasts play a key role in the pathogenesis of bone erosion and systemic bone mass loss during rheumatoid arthritis (RA). In this study, we aimed to determine the effect of methotrexate (MTX) and zoledronic acid (ZA), used alone or in combination, on osteoclast-mediated bone erosio...

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Detalles Bibliográficos
Autores principales: Le Goff, Benoit, Soltner, Elise, Charrier, Céline, Maugars, Yves, Rédini, Françoise, Heymann, Dominique, Berthelot, Jean-Marie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003529/
https://www.ncbi.nlm.nih.gov/pubmed/20003278
http://dx.doi.org/10.1186/ar2877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003529/
https://www.ncbi.nlm.nih.gov/pubmed/20003278
http://dx.doi.org/10.1186/ar2877

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