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Rituximab treatment in rheumatoid arthritis: how does it work?

Treatment with the chimerical monoclonal antibody rituximab results in CD20-directed B cell depletion. Although this depletion is almost complete in the peripheral blood of nearly all patients with rheumatoid arthritis, a proportion of patients does not exhibit a clinical response. The paper by Nako...

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Detalles Bibliográficos
Autores principales: Boumans, Maria JH, Tak, Paul P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003538/
https://www.ncbi.nlm.nih.gov/pubmed/20017888
http://dx.doi.org/10.1186/ar2852