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Liposome-Coupled Antigens Are Internalized by Antigen-Presenting Cells via Pinocytosis and Cross-Presented to CD8(+) T Cells

We have previously demonstrated that antigens chemically coupled to the surface of liposomes consisting of unsaturated fatty acids were cross-presented by antigen-presenting cells (APCs) to CD8(+) T cells, and that this process resulted in the induction of antigen-specific cytotoxic T lymphocytes. I...

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Detalles Bibliográficos
Autores principales: Tanaka, Yuriko, Taneichi, Maiko, Kasai, Michiyuki, Kakiuchi, Terutaka, Uchida, Tetsuya
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003686/
https://www.ncbi.nlm.nih.gov/pubmed/21179411
http://dx.doi.org/10.1371/journal.pone.0015225