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α-Galactosylceramide Analogs with Weak Agonist Activity for Human iNKT Cells Define New Candidate Anti-Inflammatory Agents

CD1d-restricted natural killer T cells with invariant T cell receptor α chains (iNKT cells) are a unique lymphocyte subset that responds to recognition of specific lipid and glycolipid antigens. They are conserved between mice and humans and exert various immunoregulatory functions through their rap...

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Detalles Bibliográficos
Autores principales: Bricard, Gabriel, Venkataswamy, Manjunatha M., Yu, Karl O. A., Im, Jin S., Ndonye, Rachel M., Howell, Amy R., Veerapen, Natacha, Illarionov, Petr A., Besra, Gurdyal S., Li, Qian, Chang, Young-Tae, Porcelli, Steven A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003687/
https://www.ncbi.nlm.nih.gov/pubmed/21179412
http://dx.doi.org/10.1371/journal.pone.0014374