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α-Galactosylceramide Analogs with Weak Agonist Activity for Human iNKT Cells Define New Candidate Anti-Inflammatory Agents
CD1d-restricted natural killer T cells with invariant T cell receptor α chains (iNKT cells) are a unique lymphocyte subset that responds to recognition of specific lipid and glycolipid antigens. They are conserved between mice and humans and exert various immunoregulatory functions through their rap...
Autores principales: | Bricard, Gabriel, Venkataswamy, Manjunatha M., Yu, Karl O. A., Im, Jin S., Ndonye, Rachel M., Howell, Amy R., Veerapen, Natacha, Illarionov, Petr A., Besra, Gurdyal S., Li, Qian, Chang, Young-Tae, Porcelli, Steven A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003687/ https://www.ncbi.nlm.nih.gov/pubmed/21179412 http://dx.doi.org/10.1371/journal.pone.0014374 |
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