Application of the U.S. EPA Mode of Action Framework for Purposes of Guiding Future Research: A Case Study Involving the Oral Carcinogenicity of Hexavalent Chromium

Mode of action (MOA) analysis provides a systematic description of key events leading to adverse health effects in animal bioassays for the purpose of informing human health risk assessment. Uncertainties and data gaps identified in the MOA analysis may also be used to guide future research to impro...

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Detalles Bibliográficos
Autores principales: Thompson, Chad M., Haws, Laurie C., Harris, Mark A., Gatto, Nicole M., Proctor, Deborah M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003834/
https://www.ncbi.nlm.nih.gov/pubmed/20947717
http://dx.doi.org/10.1093/toxsci/kfq320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003834/
https://www.ncbi.nlm.nih.gov/pubmed/20947717
http://dx.doi.org/10.1093/toxsci/kfq320

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