Rare familial 16q21 microdeletions under a linkage peak implicate cadherin 8 (CDH8) in susceptibility to autism and learning disability

BACKGROUND: Autism spectrum disorder (ASD) is characterised by impairments in social communication and by a pattern of repetitive behaviours, with learning disability (LD) typically seen in up to 70% of cases. A recent study using the PPL statistical framework identified a novel region of genetic li...

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Detalles Bibliográficos
Autores principales: Pagnamenta, Alistair T, Khan, Hameed, Walker, Susan, Gerrelli, Dianne, Wing, Kirsty, Bonaglia, Maria Clara, Giorda, Roberto, Berney, Tom, Mani, Elisa, Molteni, Massimo, Pinto, Dalila, Le Couteur, Ann, Hallmayer, Joachim, Sutcliffe, James S, Szatmari, Peter, Paterson, Andrew D, Scherer, Stephen W, Vieland, Veronica J, Monaco, Anthony P
Formato: Texto
Lenguaje:English
Publicado: BMJ Group 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003876/
https://www.ncbi.nlm.nih.gov/pubmed/20972252
http://dx.doi.org/10.1136/jmg.2010.079426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003876/
https://www.ncbi.nlm.nih.gov/pubmed/20972252
http://dx.doi.org/10.1136/jmg.2010.079426

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